Turkish Airlines is the national flag carrier of Turkey and one of the most expansive international airlines globally, connecting travelers from major US cities to destinations throughout Europe, Asia, Africa, the Middle East, Latin America, and the Caribbean all from its massive central hub in Istanbul (IST). The airline boasts one of Europe's largest and newest fleets of more than 530 aircraft as of early 2026. From the perspective of American travelers, Turkish Airlines stands out as one of the most strategically positioned carriers available to almost anywhere in the world: simply take an eastbound flight from New York, Chicago, Los Angeles, or Washington, D.C., connect in Istanbul, and you’ll be on your way to cities that can't be reached nonstop on any other airline. With affordable prices, renowned onboard cuisine, and a loyalty program fully integrated into the Star Alliance network, Turkish Airlines is a highly recommended option for both business and leisure travel from the US.
340+ Destinations | 130+ Countries | 6 Continents

Prior to booking your Turkish Airlines flight from the US, taking the time to understand its fare system will help you save both money and potential headaches. The airline features two primary cabin classes, Economy and Business, but also offers multiple tiers within each.
Key Point: Comparemost scans of all Turkish Airlines fare categories simultaneously along with its competitors flying the same route so you can easily and instantly identify which fare option provides the best value for your travel dates.
Unlike most carriers that prioritize routes to Western Europe or East Asia, Turkish Airlines' international network is uniquely comprehensive. As the world's third-largest international airline, its strategically positioned operations in Istanbul have cemented Turkey's status as a crucial aviation crossroads linking Europe, Asia, Africa, and the Middle East.